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Preclinical evaluation of Mito-LND, a targeting mitochondrial metabolism inhibitor, for glioblastoma treatment.

Tongxuan GuoChangyong WuLingni ZhouJunhao ZhangWanzhou WangYang ShenLudong ZhangMingshan NiuXu ZhangRutong YuXuejiao Liu
Published in: Journal of translational medicine (2023)
Taken together, the current findings support that targeting mitochondrial metabolism may be as a potential and promising strategy for GBM therapy, which will lay the theoretical foundation for further clinical trials on Mito-LND in the future.
Keyphrases
  • clinical trial
  • oxidative stress
  • cancer therapy
  • cell therapy
  • current status
  • randomized controlled trial
  • stem cells
  • risk assessment
  • combination therapy
  • replacement therapy
  • bone marrow
  • open label
  • study protocol