The Prognostic Role of CD73/A2AR Expression and Tumor Immune Response in Periampullary Carcinoma Subtypes.

Dina SweedMohammad TahaSara Abd ElhamedAsmaa Shams El Dein Mohamed

Published in: Asian Pacific journal of cancer prevention : APJCP (2022)

PDAC and AC shared CD73 Overexpression while A2AR was overexpressed in PDAC only. In PDAC, CD73 and A2AR showed an opposed prognostic effect but both had no prognostic impact on AC. In addition, tumor immune response showed a controversial impact on the prognosis of PDAC and AC.

Keyphrases

immune response
poor prognosis
nk cells
dendritic cells
transcription factor
binding protein