Predictors of Treatment Success After Periprosthetic Joint Infection: 24-Month Follow up From a Multicenter Prospective Observational Cohort Study of 653 Patients.
Joshua Saul DavisSarah MetcalfBenjamin ClarkJ Owen RobinsonPaul HugganChris LueyStephen McBrideCraig AboltinsRenjy NelsonDavid CampbellL Bogdan SolomonKellie SchneiderMark R LoewenthalPiers YatesEugene AthanDarcie CooperBabak RadTony AllworthAlistair ReidKerry ReadPeter LeungArchana SudVana NagendraRoy CheanChris LemohNora MutalimaTon TranKate GrimwadeMarjoree SehuDavid LookeAdrienne TordaThi AungSteven GravesDavid L PatersonLaurens ManningPublished in: Open forum infectious diseases (2022)
Treatment success in PJI is associated with (1) selecting the appropriate treatment strategy and (2) nonmodifiable patient and infection factors. Interdisciplinary decision making that matches an individual patient to an appropriate management strategy is a critical step for PJI management. Randomized controlled trials are needed to determine the role of rifampicin in patients managed with DAIR and the optimal surgical strategy for late-acute PJI.