Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirus.

Wei-Chen HsinChan-Hua ChangChi-You ChangWei-Hao PengChung-Liang ChienMing-Fu ChangShin C Chang

Published in: Journal of biomedical science (2018)

A MERS-oV RNA packaging signal was identified by the detection of GFP expression following an incubation of MERS VLPs carrying the heterologous mRNA GFP-PS258(19712-19969)ME with virus permissive Huh7 cells. The MERS VLP system could help us in understanding virus infection and morphogenesis.

Keyphrases

respiratory syndrome coronavirus
sars cov
coronavirus disease
binding protein
induced apoptosis
poor prognosis
cell cycle arrest
nucleic acid
protein protein
amino acid
oxidative stress
signaling pathway
cell death
saccharomyces cerevisiae
quantum dots