Serum total bile acids associate with risk of incident type 2 diabetes and longitudinal changes in glucose-related metabolic traits.

Wen ZhuShuangyuan WangHuajie DaiLiping XuanChanjuan DengTiange WangZhi-Yun ZhaoMian LiJieli LuYu XuYuhong ChenWeiqing WangYufang BiYanan HouGuang Ning

Published in: Journal of diabetes (2020)

Baseline serum TBAs were significantly associated with incident T2D and longitudinal changes in glycemic traits. Insulin resistance might partially mediate the association of TBAs and T2D.

Keyphrases

type diabetes
insulin resistance
cardiovascular disease
glycemic control
genome wide
cross sectional
adipose tissue
blood glucose
metabolic syndrome
high fat diet
skeletal muscle
polycystic ovary syndrome
blood pressure
high fat diet induced