BMI and HbA1c are metabolic markers for pancreatic cancer: Matched case-control study using a UK primary care database.
Agnieszka LemanskaClaire A PriceNathan JeffreysRachel ByfordHajira Dambha-MillerXuejuan FanWilliam HintonSophie OtterRebecca RiceAli StuntMartin B WhyteSara FaithfullSimon de LusignanPublished in: PloS one (2022)
The statistically significant changes in weight and glycaemic control started three years before pancreatic cancer diagnosis but varied according to the diabetes status. The information from this study could be used to detect pancreatic cancer earlier than is currently achieved. However, regular BMI and HbA1c measurements are required to facilitate future research and implementation in clinical practice.
Keyphrases
- primary care
- body mass index
- type diabetes
- clinical practice
- weight gain
- cardiovascular disease
- healthcare
- physical activity
- weight loss
- emergency department
- cross sectional
- glycemic control
- current status
- quality improvement
- insulin resistance
- metabolic syndrome
- adipose tissue
- skeletal muscle
- adverse drug
- health information
- social media
- drug induced
- body weight