DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53.

Muli WuduHongjiu RenLinping HuiJun JiangSiyang ZhangYitong XuQiongzi WangHongbo SuXizi JiangRuna DaoXueshan Qiu

Published in: Journal of experimental & clinical cancer research : CR (2019)

DRAM2 plays an oncogenic role in NSCLC via regulating p53 expression. Therefore, DRAM2 may act as an oncogene in NSCLC and could serve as a prognostic factor and potential target for NSCLC treatment.

Keyphrases

small cell lung cancer
prognostic factors
poor prognosis
advanced non small cell lung cancer
binding protein
transcription factor