Liquid biopsies for cancer genotyping: Coming of age?

Anders Jacobsen Skanderup Su Fen Ang Daniel Shao-Weng Tan

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)

Precision oncology is predicated on optimal molecular profiling that is "fit for purpose" to identify therapeutic vulnerabilities. Liquid biopsies may compensate for inadequate genotyping, but remain less sensitive and specific compared to tissue biopsies. The liquid biopsy toolbox is poised to expand through novel assays and insights from longitudinal profiling.

Keyphrases

ultrasound guided
high throughput
ionic liquid
single cell
genome wide
papillary thyroid
palliative care
fine needle aspiration
cross sectional
squamous cell carcinoma
squamous cell
gene expression
dna methylation
young adults