A multidisciplinary approach to mental illness: do inflammation, telomere length and microbiota form a loop? A protocol for a cross-sectional study on the complex relationship between inflammation, telomere length, gut microbiota and psychiatric disorders.
Mirko ManchiaPasquale ParibelloCarlo ArzediAlberto BocchettaPaola CariaCristina CoccoDonatella CongiuEleonora CossuTinuccia DettoriDaniela V FrauMario GarzilliElias MancaAnna MeloniMaria A MontisAndrea MuraMariella NiedduBarbara NoliFederica PinnaClaudia PisanuRenato RobledoGiovanni SeverinoValeria SogosCaterina ChillottiBernardo CarpinielloMaria Del ZompoGian Luca FerriRoberta VanniAlessio SquassinaPublished in: BMJ open (2020)
The study protocol was approved by the Ethics Committee of the University Hospital Agency of Cagliari (PG/2018/11693, 5 September 2018). The study is conducted in accordance with the principles of good clinical practice and the Declaration of Helsinki, and in compliance with the relevant Italian national legislation. Written, informed consent is obtained from all participants. Participation in the study is on a voluntary basis only. Patients will be part of the dissemination phase of the study results, during which a local conference will be organised and families of patients will also be involved. Moreover, findings will be published in one or more research papers and presented at national and international conferences, in posters or oral communications.