The effects of fatty acids consumption on OPG/RANKL/RANK system in cardiovascular diseases: Current status and future perspectives for the impact of diet-gene interaction.
Omid Reza TamtajiShokoofeh BorzabadiMajid Ghayour MobarhanGordon FernsZatollah AsemiPublished in: Journal of cellular biochemistry (2018)
Cardiovascular disease (CVD) is an overall term that comprises a number of related pathologies, these include peripheral arterial disease, cerebrovascular disease, coronary heart disease (CHD), venous thromboembolism, and rheumatic and congenital heart diseases. Fatty acids in the diet have been reported to affect CVD. The OPG/RANKL/RANK system appears to have a role in CVD outcomes. However, there have been few studies on the impact of diet-gene interaction for effects of fatty acids consumption on the OPG/RANKL/RANK system in CVD. This review focuses on the effects of fatty acids on OPG/RANKL/RANK in CVD.
Keyphrases
- fatty acid
- cardiovascular disease
- venous thromboembolism
- physical activity
- nuclear factor
- weight loss
- bone loss
- current status
- copy number
- preterm infants
- cardiovascular events
- toll like receptor
- dna methylation
- gene expression
- metabolic syndrome
- coronary artery disease
- atrial fibrillation
- inflammatory response
- genome wide analysis