The effects of pantoprazole vs. placebo on 1-year outcomes, resource use and employment status in ICU patients at risk for gastrointestinal bleeding: a secondary analysis of the SUP-ICU trial.
Christine Marie Bækø HallingMorten Hylander MöllerSøren MarkerMette KragJakob KjellbergAnders PernerDorte Gyrd-HansenPublished in: Intensive care medicine (2022)
Among ICU patients at risk of GI bleeding, pantoprazole reduced clinically important GI bleeding in ICU, but this did not translate into a reduction in 1-year mortality, health care resource use or improvements in employment status.
Keyphrases
- intensive care unit
- mechanical ventilation
- end stage renal disease
- healthcare
- chronic kidney disease
- newly diagnosed
- atrial fibrillation
- phase iii
- ejection fraction
- clinical trial
- peritoneal dialysis
- prognostic factors
- cardiovascular events
- study protocol
- acute respiratory distress syndrome
- mental illness
- randomized controlled trial
- coronary artery disease
- mental health
- metabolic syndrome
- insulin resistance
- social media
- extracorporeal membrane oxygenation
- patient reported
- health information