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Do condensed tannins from Lysiloma latisiliquum have a role in its anthelmintic activity?

Carlos Alfredo Sandoval-Castro
Published in: Natural product research (2017)
We would like to comment on a recent paper by Hernandez-Bolio et al. (2017, Nat. Prod. Res. DOI: 10.1080/14786419.2017.1317774) where an extract free of condensed tannin (CT) was evaluated and concluded that Lysiloma latisiliquum CT does not have a role in its anthelmintic (AH) activity. This letter discusses the AH potential of L. latisiliquum based on previously published evidence of a partial role of CT using different AH assays and Haemonchus contortus isolates. Because the experimental design employed in the above-mentioned paper did not allow a clear-cut conclusion regarding the role of CT, this suggests that a specific experiment must be designed to confirm or reject the involvement of CT fraction(s) on L. latisiliquum AH activity.
Keyphrases
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  • dual energy
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  • positron emission tomography
  • magnetic resonance imaging
  • systematic review
  • randomized controlled trial
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  • high throughput