Medication changes implemented during medication reviews and factors related to deprescribing: post-hoc analyses of a randomized clinical trial in geriatric outpatients with polypharmacy.

Jonatan KornholtShafika Tapia FeiziAlexandra Storm HansenJannie Thaysen LaursenKarl Sebastian JohanssonLene Ørskov ReutherTonny Studsgaard PetersenEckart PresselMikkel Bring Christensen

Published in: British journal of clinical pharmacology (2023)

Physician-led medication reviews resulted in persistent deprescribing of medicines in older polypharmacy patients treated with ≥9 medicines. Motivation for having their medicine changed, treatment with more medicines, and a higher burden of sedative and anticholinergic medicines characterized the patients most likely to benefit from physician-led medication reviews.

Keyphrases

adverse drug
healthcare
end stage renal disease
emergency department
primary care
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
randomized controlled trial
physical activity
systematic review
patient reported outcomes