Expression and clinical significance of PD-L1, B7-H3, B7-H4 and VISTA in craniopharyngioma.

Yuelong WangJiaojiao DengLin WangTingyue ZhouJinlong YangZerong TianJinhao YangHongxu ChenXin TangShasha ZhaoLiangxue ZhouAiping TongJianGuo Xu

Published in: Journal for immunotherapy of cancer (2021)

We found variable expression of PD-L1, B7-H3, B7-H4 and VISTA proteins in CPs. The results suggest that the expression level of VISTA may be used as an important indicator to predict the OS and PFS of CPs. B7 family ligands/receptors could be potential immunotherapeutic targets when treating CPs.

Keyphrases

poor prognosis
binding protein