Incidence of Small Intestinal Bacterial Overgrowth and Symptoms After 7 Days of Proton Pump Inhibitor Use: A Study on Healthy Volunteers.
Cristina Durán-RosasBryan Adrián Priego-ParraEliana Morel-CerdaLydia A Mercado-JaureguiCarlos Arturo Aquino-RuizArturo Triana-RomeroMercedes Amieva-BalmoriJosé Antonio Velarde-Ruiz VelascoJosé María Remes-TrochePublished in: Digestive diseases and sciences (2023)
Our study showed that a short-term 7-day PPI course produced SIBO in 7.8% of healthy subjects. Although, inappropriate use of PPIs should be discouraged, but since more than 90% of subjects who received PPIs for one week did not develop SIBO, the advantages of PPI administration seem to outweigh the disadvantages.