Perioperative goal-directed therapy: A systematic review without meta-analysis.
Thomas KaufmannRamon P ClementThomas W L ScheerenBernd SaugelFrederik KeusIwan C C van der HorstPublished in: Acta anaesthesiologica Scandinavica (2018)
Clinical heterogeneity in patients, interventions and outcomes in perioperative goal-directed therapy trials is too large to perform meta-analysis on all trials. Future trials and meta-analyses highly depend on universally agreed definitions on aspects beyond type of surgery of the complex intervention and its evaluation.
Keyphrases
- meta analyses
- systematic review
- randomized controlled trial
- end stage renal disease
- patients undergoing
- cardiac surgery
- chronic kidney disease
- ejection fraction
- minimally invasive
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- type diabetes
- case control
- single cell
- coronary artery disease
- metabolic syndrome
- skeletal muscle
- insulin resistance