Pharmacokinetics, pharmacodynamics and safety assessment of multiple doses of soticlestat in healthy volunteers.

Shining WangGrace ChenEmilio Merlo PichJohn AffinitoMichael CwikHélène M Faessel

Published in: British journal of clinical pharmacology (2022)

The pharmacokinetic and pharmacodynamic profiles of soticlestat characterized here provided a data-driven rationale for clinical trial dose selection.

Keyphrases

clinical trial
phase ii
open label
study protocol
phase iii
randomized controlled trial