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Heparin-Induced Thrombocytopenia: A Review of New Concepts in Pathogenesis, Diagnosis, and Management.

Matteo MarchettiMaxime G ZermattenDebora Bertaggia CalderaraAlessandro AliottaLorenzo Alberio
Published in: Journal of clinical medicine (2021)
Knowledge on heparin-induced thrombocytopenia keeps increasing. Recent progress on diagnosis and management as well as several discoveries concerning its pathogenesis have been made. However, many aspects of heparin-induced thrombocytopenia remain partly unknown, and exact application of these new insights still need to be addressed. This article reviews the main new concepts in pathogenesis, diagnosis, and management of heparin-induced thrombocytopenia.
Keyphrases
  • high glucose
  • diabetic rats
  • venous thromboembolism
  • growth factor
  • drug induced
  • randomized controlled trial
  • systematic review
  • endothelial cells
  • oxidative stress
  • molecular dynamics