Altered gene expression of VEGF, IGFs and H19 lncRNA and epigenetic profile of H19-DMR region in endometrial tissues of women with endometriosis.

Sedigheh KamraniElham AmirchaghmaghiFirouzeh GhaffariMaryam ShahhoseiniKamran Ghaedi

Published in: Reproductive health (2022)

These data showed that VEGF, IGF1, IGF2 and H19 lncRNA genes expression and epigenetic alterations of H19 lncRNA have dynamic role in the pathogenesis of endometriosis, specifically in the way that hypomethylation of H19-DMR region II can be involved in IGF2 dysregulation in endometriosis.

Keyphrases

gene expression
dna methylation
binding protein
long non coding rna
vascular endothelial growth factor
poor prognosis
pi k akt
long noncoding rna
endothelial cells
growth hormone
genome wide
big data
cell proliferation
signaling pathway
endometrial cancer
machine learning
artificial intelligence