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Expression of mitochondrial dysfunction-related genes and pathways in paclitaxel-induced peripheral neuropathy in breast cancer survivors.

Kord M KoberAdam OlshenYvettte P ConleyMark SchumacherKimberly ToppBetty SmootMelissa MazorMargaret ChesneyMarilyn HammerSteven M PaulJon D LevineChristine Miaskowski
Published in: Molecular pain (2018)
This study is the first to provide molecular evidence that a number of mitochondrial dysfunction mechanisms identified in preclinical models of various types of neuropathic pain including chemotherapy-induced peripheral neuropathy are found in breast cancer survivors with persistent PIPN and suggest genes for validation and as potential therapeutic targets.
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