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Immune Checkpoint Blockade Outcome in Small-Cell Lung Cancer and Its Relationship With Retinoblastoma Mutation Status and Function.

Afshin DowlatiAta AbbasTimothy ChanBrian S HenickXuya WangParul DoshiPingfu FuJyoti D PatelFengshen KuoHan ChangDavid Balli
Published in: JCO precision oncology (2022)
WT status or lower RB1 LOF signature scores by transcriptomics have better outcomes with ICB monotherapy.
Keyphrases
  • small cell lung cancer
  • single cell
  • open label
  • randomized controlled trial
  • clinical trial
  • skeletal muscle
  • adipose tissue
  • study protocol