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A phase II randomized trial of talimogene laherparepvec oncolytic immunotherapy with or without radiotherapy for patients with cutaneous metastases from solid tumors.

Christopher A BarkerSandra P D'AngeloGloria WasilewskiAlexa M StecklerMing LianZhigang ZhangPaul B ChapmanAlexander N ShoushtariCharlotte E Ariyan
Published in: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology (2024)
Low overall response rate, slow accrual, and the COVID-19 pandemic led to closure of this trial. Responses in non-injected and non-irradiated metastases were infrequent.
Keyphrases
  • phase ii
  • clinical trial
  • open label
  • phase iii
  • early stage
  • placebo controlled
  • double blind
  • radiation therapy
  • locally advanced
  • study protocol
  • radiation induced
  • randomized controlled trial