Mechanistic insight into activation of MAPK signaling by pro-angiogenic factors.
Min SongStacey D FinleyPublished in: BMC systems biology (2018)
The model agrees with experimental data and is a framework to synthesize and quantitatively explain experimental studies. Ultimately, the model provides mechanistic insight into FGF and VEGF interactions needed to identify potential targets for pro- or anti-angiogenic therapies.