Role of irisin in effects of chronic exercise on muscle and bone in ovariectomized mice.

Naoyuki KawaoShunki IemuraMiku KawaguchiYuya MizukamiYoshimasa TakafujiHiroshi Kaji

Published in: Journal of bone and mineral metabolism (2021)

We demonstrated that chronic exercise elevated irisin expression in the gastrocnemius and soleus muscles of estrogen-deficient mice. Irisin might be related to increases in trabecular BMD in mice; however, further studies are needed to clarify the involvement of irisin in the effects of chronic exercise on muscle/bone interactions.

Keyphrases

high intensity
bone mineral density
physical activity
skeletal muscle
resistance training
bone loss
high fat diet induced
poor prognosis
postmenopausal women
type diabetes
insulin resistance
long non coding rna
bone regeneration
case control