Comparison of real world and core laboratory lupus anticoagulant results from the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) clinical database and repository.
Maria EfthymiouIan J MackiePhilip J LaneDanieli AndradeRohan WillisDoruk ErkanSavinio SciasciaSteven KrillisElisa BisonMargarete Borges Galhardo VendraminiZurina Romay-PenabadMiao QiMaria G G TektonidouAmaia UgarteCecilia ChighizolaH Michael BelmontMaria Angeles AguirreLanlan JiD Ware BranchGuilherme de JesusPaul R FortinLaura AndreoliMichelle PetriRicard CerveraEsther RodriguezChristian LoodTatsuya AtsumiJoann VegaEcem SevimMaria Laura BertolacciniVittorio PengoHannah Cohennull nullPublished in: Journal of thrombosis and haemostasis : JTH (2019)
Laboratories can achieve good agreement in LA performance by use of the same reagents, analyzer type, and protocols. The standardized Core laboratory results underpin accurate interpretation of APS ACTION clinical data.