The patient-reported outcome content of international ovarian cancer randomised controlled trial protocols.
Rebecca Mercieca-BebberMichael FriedlanderPeey-Sei KokMelanie CalvertDerek KyteMartin StocklerMadeleine T KingPublished in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2016)
On average, protocols addressed less than one-third of PRO protocol checklist items. In some cases, key guidance regarding PRO administration was lacking, which may lead to inconsistent and sub-optimal PRO methodology. Efforts are needed to improve PRO protocol content in cancer trials.