A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta.

Amy M InksterVictor YuanChaini KonwarAllison M MatthewsCarolyn J BrownWendy P Robinson

Published in: Biology of sex differences (2021)

Our results provide a comprehensive analysis of sex differences in autosomal DNAme in the term human placenta. We report a list of high-confidence autosomal sex-associated differentially methylated CpGs and identify several key features of these loci that suggest their relevance to sex differences observed in normative and complicated pregnancies.

Keyphrases

gestational age
dna methylation
genome wide
preterm infants
endothelial cells
gene expression
preterm birth
induced pluripotent stem cells
pluripotent stem cells
pregnant women
pregnancy outcomes
genome wide association