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Pulse oximetric saturation to fraction of inspired oxygen (SpO2/FIO2) ratio 24 hours after high-flow nasal cannula (HFNC) initiation is a good predictor of HFNC therapy in patients with acute exacerbation of interstitial lung disease.

Takafumi KoyauchiHideki YasuiNoriyuki EnomotoHirotsugu HasegawaHironao HozumiYuzo SuzukiMasato KarayamaKazuki FuruhashiTomoyuki FujisawaYutaro NakamuraNaoki InuiKoshi YokomuraTakafumi Suda
Published in: Therapeutic advances in respiratory disease (2021)
HFNC was well tolerated in patients with AE-ILD, suggesting that HFNC is a reasonable respiratory management for these patients. The SpO2/FIO2 ratio 24 h after initiating HFNC was a good predictor of successful HFNC treatment. The reviews of this paper are available via the supplemental material section.
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