Childhood Obesity Is Associated With Subclinical Left Ventricular Dysfunction Detected by Speckle Tracking Echocardiography.
Bahar DehghanMohsen SedighiNoushin RostampourElham HashemiSilva HovsepianMohammad Reza SabriMehdi GhaderianChehreh MahdaviAlireza AhmadiAzadeh EsnaashariPublished in: Clinical pediatrics (2023)
Childhood obesity is related to cardiac structural and functional changes, increasing the risk of heart disease. Sixty normotensive children were assigned based on body mass index (BMI) into normal weight, overweight, and obese groups and examined by two-dimensional speckle tracking echocardiography (2D-STE). Weight ( P = .001) and BMI ( P = .001) differed significantly among the 3 groups. Left ventricular (LV) strain ( P = .001) and strain rate ( P = .002) in overweight and obese children ( P = .001) were significantly lower compared to normal weight group. LV mass in obese children was notably larger compared to overweight children ( P = .047). LV strain was associated with age ( P = .031), weight ( P = .001), and height ( P = .022). There was an association between LV strain rate with weight ( P = .001) and between left atrial area and height of children ( P = .007). Obesity in normotensive obese children is associated with subclinical alteration of LV dimension and myocardial longitudinal strain recognized by 2D-STE.
Keyphrases
- body mass index
- left ventricular
- weight loss
- weight gain
- young adults
- physical activity
- left atrial
- metabolic syndrome
- heart failure
- bariatric surgery
- type diabetes
- computed tomography
- adipose tissue
- hypertrophic cardiomyopathy
- pulmonary hypertension
- coronary artery disease
- oxidative stress
- acute myocardial infarction
- cardiac resynchronization therapy
- insulin resistance
- body weight
- acute coronary syndrome
- cross sectional
- obese patients
- transcatheter aortic valve replacement