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Exploring the Evidence for Broad-Spectrum Effectiveness of Perampanel: A Systematic Review of Clinical Data in Generalised Seizures.

Eugen TrinkaSimona LattanziKate CarpenterTommaso CorradettiBruna NuceraFabrizio RinaldiRohit ShankarFrancesco Brigo
Published in: CNS drugs (2021)
The identified studies suggest the potential of perampanel as a broad-spectrum antiseizure medication. Much of the available data, however, come from non-randomised, non-controlled studies and are open to high risk of bias. Further studies are warranted to provide more robust evidence.
Keyphrases
  • case control
  • electronic health record
  • clinical trial
  • randomized controlled trial
  • systematic review
  • open label
  • minimally invasive
  • data analysis
  • placebo controlled