Exploring the Evidence for Broad-Spectrum Effectiveness of Perampanel: A Systematic Review of Clinical Data in Generalised Seizures.
Eugen TrinkaSimona LattanziKate CarpenterTommaso CorradettiBruna NuceraFabrizio RinaldiRohit ShankarFrancesco BrigoPublished in: CNS drugs (2021)
The identified studies suggest the potential of perampanel as a broad-spectrum antiseizure medication. Much of the available data, however, come from non-randomised, non-controlled studies and are open to high risk of bias. Further studies are warranted to provide more robust evidence.