The REVAMP trial to evaluate HIV resistance testing in sub-Saharan Africa: a case study in clinical trial design in resource limited settings to optimize effectiveness and cost effectiveness estimates.
Mark J SiednerMwebesa B BwanaMahomed-Yunus S MoosaMichelle PaulSelvan PillaySuzanne McCluskeyIsaac AturindaKevin ArdWinnie MuyindikePravikrishnen MoodleyJaysingh BrijkumarTamlyn RautenbergGavin GeorgeBrent JohnsonRajesh T GandhiHenry SunpathVincent C MarconiPublished in: HIV clinical trials (2017)
REVAMP is a pragammatic randomized clinical trial designed to test the effectiveness and cost-effectiveness of HIV resistance testing versus standard of care in sub-Saharan Africa. We anticipate the results will directly inform HIV policy in sub-Saharan Africa to optimize care for HIV-infected patients.
Keyphrases
- antiretroviral therapy
- hiv infected patients
- hiv infected
- hiv positive
- human immunodeficiency virus
- clinical trial
- healthcare
- hiv testing
- hiv aids
- randomized controlled trial
- hepatitis c virus
- men who have sex with men
- palliative care
- quality improvement
- systematic review
- study protocol
- public health
- phase ii
- double blind
- phase iii
- pain management