The role of NPM1 alternative splicing in patients with chronic lymphocytic leukemia.
Monika SzelestMarta MasternakMałgorzata ZającMichał ChojnackiKatarzyna SkórkaJoanna ZaleskaAgnieszka KarczmarczykGrażyna StasiakEwa WawrzyniakAleksandra KotkowskaMonika Siemieniuk-RyśJoanna PurkotEdyta SuboczEdyta CichockaWaldemar TomczakDaria ZawirskaKrzysztof GiannopoulosPublished in: PloS one (2022)
In conclusion, our study indicates the prognostic significance of the level of NPM1.R1 expression and suggests the importance of splicing alterations in the pathogenesis of CLL.