Pre-eclampsia is associated with reduced resolvin D1 and maresin 1 to leukotriene B4 ratios in the plasma.
Luiza Oliveira PerucciTalita Adriana Pereira Dos SantosPatrícia Campi SantosLívia Cristina Ribeiro TeixeiraPatrícia Nessralla AlpoimKarina Braga GomesLirlândia Pires SousaLuci Maria Sant'Ana DusseAndre TalvaniPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2019)
Our findings suggest that the PE state results in systemic overproduction of LTB4 in relation to RvD1 and MaR1, and that these lipid mediators may be involved with the disease pathogenesis.
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