High Expression of Adrenal Cortisol Synthases Is Acquired After Intrauterine Inflammation in Periviable Sheep Fetuses.
Shinichi SatoShimpei WatanabeYuya SaitoAika TakanashiHideyuki IkedaYoshie SakuraiShouta KoshinamiYusaku KumagaiHaruo UsudaTakushi HanitaAtsuo KikuchiMasatoshi SaitoPublished in: Journal of the Endocrine Society (2023)
Periviable fetuses exposed to inflammation in utero have altered the responsiveness of the HPA axis with increased expression of enzymes involved in cortisol synthesis in the adrenal gland.