Longitudinal bone microarchitectural changes are best detected using image registration.

T D KempC M J de BakkerL GabelD A HanleyE O BillingtonL A BurtSteven K Boyd

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2020)

At least SM or 3DR should be implemented in longitudinal studies using HR-pQCT. 3DR is preferable, particularly at the radius, to ensure that physiological changes in bone density are observed.

Keyphrases

bone mineral density
editorial comment
soft tissue
cross sectional
bone loss
bone regeneration
deep learning
postmenopausal women
cone beam