Maternal immune activation alters brain microRNA expression in mouse offspring.

Jun-Sang SunwooDaejong JeonSoon-Tae LeeJangsup MoonJung-Suk YuDong-Kyu ParkJi-Yeon BaeDoo Young LeeSangwoo KimKeun Hwa JungKyung-Il ParkKi-Young JungManho KimSang Kun LeeKon Chu

Published in: Annals of clinical and translational neurology (2018)

Our results provide novel information regarding miRNA expression changes and their putative targets in the early postnatal period of brain development. Further studies will be needed to evaluate potential pathogenic roles of the dysregulated miRNAs.

Keyphrases

poor prognosis
resting state
white matter
binding protein
functional connectivity
preterm infants
high fat diet
cerebral ischemia
type diabetes
risk assessment
pregnant women
adipose tissue
brain injury
case control
blood brain barrier