Differential infectivity of gametocytes after artemisinin-based combination therapy of uncomplicated falciparum malaria.

Dinkorma T Ouologuem Cheick O Kone Bakary Fofana Bakary Sidibe Amadou H Togo Demba Dembele Sekou Toure Sekou Koumare Ousmane Toure Issaka Sagara Abdoulaye Toure Adama Dao Ogobara K Doumbo Abdoulaye A Djimde

Published in: African journal of laboratory medicine (2018)

Different ACT regimens could lead to gametocyte populations with different capacity to infect the Anopheles vector. Frequent assessment of the effect of antimalarials on gametocytogenesis and gametocyte infectivity may be required for the full assessment of treatment efficacy, the potential for spread of drug resistance and malaria transmission in the field.

Keyphrases

plasmodium falciparum
combination therapy
risk assessment
urinary tract infection
human health
replacement therapy