BMP-6 and SMAD4 gene expression is altered in cumulus cells from women with endometriosis-associated infertility.

Emily De Conto Ursula da Silveira Matte João Sabino Lahorgue da Cunha Filho

Published in: Acta obstetricia et gynecologica Scandinavica (2020)

The reduced expression of BMP-6 and SMAD4 in women with peritoneal endometriosis compared with the control group indicates that granulosa (cumulus) cell function could be altered in these women.

Keyphrases

polycystic ovary syndrome
gene expression
epithelial mesenchymal transition
transforming growth factor
mesenchymal stem cells
poor prognosis
insulin resistance
bone regeneration
dna methylation
pregnancy outcomes
binding protein
adipose tissue