Non-invasive ventilation versus high-flow nasal oxygen for postextubation respiratory failure in ICU: a post-hoc analysis of a randomized clinical trial.

Arnaud W ThilleGrégoire MonseauRémi CoudroyMai-Anh NayArnaud GacouinMaxens DecavèleRomain SonnevilleFrançois BeloncleChristophe GiraultLaurence DangersAlexandre LautretteQuentin LevratAnahita RouzéEmmanuel VivierJean-Baptiste LascarrouJean-Damien RicardKeyvan RazaziGuillaume BarberetChristine LebertStephan EhrmannAlexandre MassriJeremy BourenneGael PradelPierre BaillyNicolas TerziJean DellamonicaGuillaume LacaveRené RobertStéphanie RagotJean-Pierre Fratnull null

Published in: Critical care (London, England) (2021)

In patients with post-extubation respiratory failure, NIV alternating with high-flow nasal oxygen might not increase the risk of death. Trial registration number The trial was registered at http://www.clinicaltrials.gov with the registration number NCT03121482 the 20th April 2017.

Keyphrases

respiratory failure
mechanical ventilation
extracorporeal membrane oxygenation
phase iii
study protocol
phase ii
acute respiratory distress syndrome
intensive care unit
clinical trial
chronic rhinosinusitis
open label
randomized controlled trial