Intraoperative use of fluorescence with indocyanine green reduces anastomotic leak rates in rectal cancer surgery: an individual participant data analysis.
Alberto ArezzoMarco Augusto BoninoFrédéric RisLuigi BoniElisa CassinottiDominic Chi Chung FooNga Fan ShumAlberto BroleseFrancesco CiarleglioDeborah S KellerRiccardo RosatiPaola De NardiUgo ElmoreUberto Fumagalli RomarioMehraneh Dorna JafariAlessio PigazziEvgeny RybakovMikhail AlekseevJun WatanabeNereo VettorettoRoberto CirocchiRoberto PasseraEdoardo ForcignanòMario MorinoPublished in: Surgical endoscopy (2020)
The incidence of AL may be reduced when ICG fluorescence imaging is used to assess the perfusion of a colorectal anastomosis. Limitations relate to the consistent number of non-randomized studies included and their heterogeneity in defining and assessing AL. Ongoing large randomized studies will help to determine the exact role of routine ICG fluorescence imaging may decrease the incidence of AL in surgery for rectal cancer.
Keyphrases
- fluorescence imaging
- rectal cancer
- data analysis
- photodynamic therapy
- locally advanced
- minimally invasive
- coronary artery bypass
- double blind
- open label
- placebo controlled
- risk factors
- phase iii
- phase ii
- case control
- surgical site infection
- clinical trial
- randomized controlled trial
- single cell
- clinical practice
- single molecule
- magnetic resonance imaging
- percutaneous coronary intervention
- density functional theory
- atrial fibrillation
- acute coronary syndrome