State of the art of patient-reported outcomes in acromegaly or GH deficiency: a systematic review and meta-analysis.

Merel van der Meulen Amir H Z NajafabadiLeonie H A BroersenJan W SchoonesAlberto M PereiraWouter R van FurthKim M J A ClaessenNienke R Biermasz

Published in: The Journal of clinical endocrinology and metabolism (2021)

Prospective studies among patients with acromegaly and GHD use a multitude of PROMs, often poorly reported. Since a substantial proportion of studies report discrepancies between PROs and biochemical outcomes, PROMs are pivotal in the evaluation of disease activity. Therefore, harmonization of PROs in clinical practice and research by development of Core Outcome Sets is an important unmet need.

Keyphrases

patient reported outcomes
disease activity
systemic lupus erythematosus
rheumatoid arthritis
clinical practice
growth hormone
rheumatoid arthritis patients
ankylosing spondylitis
case control
type diabetes
adipose tissue
metabolic syndrome
skeletal muscle
insulin resistance
replacement therapy