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A systematic review of case series and clinical trials investigating systemic oral or injectable therapies for the treatment of vitiligo.

Alireza JafarzadehArash Pour MohammadMina KhosraviShila AmiriAsma RasouliHaniyeh KeramatiAzadeh Goodarzi
Published in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2024)
Systemic treatments for vitiligo have been successful in controlling lesions without notable side effects. OMP, Methotrexate, Azathioprine, Cyclosporine, Mycophenolate mofetil, Simvastatin, Apremilast, Minocycline, Afamelanotide, Tofacitinib, Baricitinib, Antioxidants, and oral/injectable corticosteroids are effective treatment methods. However, oral zinc and alefacept did not show effectiveness.
Keyphrases
  • clinical trial
  • systematic review
  • randomized controlled trial
  • hyaluronic acid
  • tissue engineering