Impact of obesity on clinical outcomes in hormone receptor-positive breast cancer: a systematic review.
Melika ShirdarrehRossanna C PezoPublished in: Breast cancer (Tokyo, Japan) (2021)
The results of our systematic review highlight a need for further research exploring the optimal endocrine therapies for obese women. There is insufficient evidence at present to recommend tailoring adjuvant endocrine therapy with use of specific AIs or for dosing modifications of AIs in this patient population.
Keyphrases
- positive breast cancer
- systematic review
- weight loss
- metabolic syndrome
- type diabetes
- insulin resistance
- meta analyses
- polycystic ovary syndrome
- adipose tissue
- early stage
- case report
- bariatric surgery
- weight gain
- high fat diet induced
- pregnancy outcomes
- randomized controlled trial
- obese patients
- breast cancer risk
- skeletal muscle
- cervical cancer screening
- body mass index
- mesenchymal stem cells
- bone marrow
- cell therapy
- smoking cessation