[Choroidal changes in patients with diabetes mellitus].
Anait S KhalatyanYusef YusefPublished in: Vestnik oftalmologii (2024)
Diabetic retinopathy (DR) is a microvascular complication of diabetes mellitus (DM) and considered one of the leading causes of vision loss worldwide. The choroid supplies blood to the retina, photoreceptors and the retinal pigment epithelium, it is essential for metabolic exchange in the retina. Many experimental studies have reported that choroidal pathology in diabetic patients may play a role in the development of DR. Choroidal thickness (CT) can be used to assess the vascularization of the choroid. Choroidal vascularity index (CVI) is also used as a marker in assessment of choroidal vascularization. Many studies have been conducted to evaluate choroidal changes in various eye diseases. However, the data on CT in DM patients, especially in those with DR, are conflicting. Thus, the choroidal status in diabetic patients with or without DR remains controversial. In this systematic review we analyze a number of articles dedicated to the relationship between structural changes in the choroid in patients with diabetes mellitus and diabetic retinopathy of different stages, paying particular attention to choroidal thickness and certain other parameters that allow assessment of choroidal changes.
Keyphrases
- optical coherence tomography
- diabetic retinopathy
- optic nerve
- systematic review
- age related macular degeneration
- computed tomography
- end stage renal disease
- randomized controlled trial
- chronic kidney disease
- type diabetes
- ejection fraction
- magnetic resonance imaging
- working memory
- prognostic factors
- contrast enhanced
- machine learning
- positron emission tomography
- peritoneal dialysis
- big data
- patient reported outcomes