The role of S100A12 and Toll-like receptor 4 in assessment of disease activity in familial Mediterranean fever and juvenile idiopathic arthritis.
Seyma DumurAmra AdrovicKenan BarutOzgur KasapcopurMine KucurPublished in: International journal of rheumatic diseases (2022)
Serum S100A12 levels were not found to be a potentially valuable biomarker for assessing disease activity in either FMF or JIA. However, TLR4 levels were found to be a valuable biomarker for assessing disease activity in children with FMF. Further research which includes serial monitoring of S100A12 and TLR4 levels in a large cohort will provide detailed information about accuracy of these 2 potential biomarkers in both patients group.
Keyphrases
- disease activity
- juvenile idiopathic arthritis
- toll like receptor
- systemic lupus erythematosus
- rheumatoid arthritis
- rheumatoid arthritis patients
- ankylosing spondylitis
- inflammatory response
- nuclear factor
- end stage renal disease
- immune response
- chronic kidney disease
- newly diagnosed
- ejection fraction
- peritoneal dialysis
- early onset
- social media
- patient reported