Effect of duration of adjuvant chemotherapy with S-1 (6 versus 12 months) for resected pancreatic cancer: the multicenter clinical randomized phase II postoperative adjuvant chemotherapy S-1 (PACS-1) trial.

Hiroto KayashimaShinji ItohMototsugu ShimokawaHiromitsu HayashiHiroshi TakamoriKengo FukuzawaMizuki NinomiyaKenichiro ArakiYo-Ichi YamashitaKeishi SugimachiHideaki UchiyamaYuji MorineTohru UtsunomiyaTadashi UwagawaTakashi MaedaHideo BabaTomoharu Yoshizumi

Published in: International journal of clinical oncology (2023)

In patients with resected pancreatic cancer, 12-month adjuvant chemotherapy with S-1 was not superior to 6-month therapy regarding OS and DFS.

Keyphrases

phase ii
double blind
open label
clinical trial
phase iii
placebo controlled
lymph node
patients undergoing
study protocol
cross sectional
bone marrow
smoking cessation