Tumor mutation burden as a biomarker in resected gastric cancer via its association with immune infiltration and hypoxia.

Deqiang WangNing WangXiaoqin LiXiaofeng ChenBo ShenDongqin ZhuLiuqing ZhuYaping XuYangyang YuYongqian Shu

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2021)

High TMB may predict favorable prognosis in resected GC but poor response to postoperative CT/RCT in stage Ib/II subgroup, which may be determined by TMB-associated immune infiltration and hypoxia, respectively.

Keyphrases

lymph node
endothelial cells
computed tomography
patients undergoing
prognostic factors
image quality
dual energy
magnetic resonance imaging
randomized controlled trial
clinical trial
positron emission tomography
mass spectrometry