Genetic correlation of the plasma lipidome with type 2 diabetes, prediabetes and insulin resistance in Mexican American families.
Hemant KulkarniManju MamtaniGerard WongJacquelyn M WeirChristopher K BarlowThomas D DyerLaura AlmasyMichael C MahaneyAnthony G ComuzzieRavindranath DuggiralaPeter J MeikleJohn BlangeroJoanne E CurranPublished in: BMC genetics (2017)
Our results imply that: a) not all plasma lipid species are genetically informative for T2D pathogenesis; b) the DAG and TAG lipid classes partially share genetic basis of T2D; and c) 1-palmitate containing TAGs may provide additional insights into the genetic basis of T2D.