Interaction among dietary n-3 and n-6 polyunsaturated fatty acid intake, fatty acid desaturase 2 genetic variants, and low-density lipoprotein cholesterol levels in type 2 diabetes patients.
Pei-Chi HuangHsuan ChengYu-Ting SuMeng-Chuan HuangChih-Cheng HsuShang-Jyh HwangShyi-Jang ShinWen-Tsan ChangPublished in: Journal of diabetes investigation (2022)
Our results show the role of n-3/n-6 dietary polyunsaturated fatty acids in modifying the effects of genetic susceptibility on lipoprotein concentrations in patients with type 2 diabetes. Our findings highlight the potential of interventions with dietary polyunsaturated fatty acids regarding developing individualized prevention strategies for type 2 diabetes presenting with co-occurring dyslipidemia and cardiovascular diseases.
Keyphrases
- fatty acid
- type diabetes
- cardiovascular disease
- end stage renal disease
- ejection fraction
- glycemic control
- newly diagnosed
- insulin resistance
- physical activity
- prognostic factors
- case report
- coronary artery disease
- dna methylation
- gene expression
- risk assessment
- climate change
- body mass index
- adipose tissue
- human health
- weight gain
- weight loss