[Inhibition of connexin 43-mediated hemichannel activity promotes odontoblast differentiation of human dental pulp cells induced by lipopolysaccharide].

An-Ni ZhangCan-Can DingLi-Ping HuangShi-Ting Li

Published in: Shanghai kou qiang yi xue = Shanghai journal of stomatology (2024)

Cx43 participates in the regulation of dental pulp repair after injury, and its expression shows a downward trend as a whole. Inhibition of Cx43 or blocking of HC promotes LPS-induced ERK signal activity and odontoblast differentiation of hDPCs.

Keyphrases

lps induced
inflammatory response
induced apoptosis
endothelial cells
poor prognosis
signaling pathway
cell cycle arrest
pi k akt
oxidative stress
cell death